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Image Search Results
Journal: Journal of neuroscience methods
Article Title: An optimized method for purification of whole brain-derived extracellular vesicles reveals insight into neurodegenerative processes in a mouse model of Alzheimer’s disease.
doi: 10.1016/j.jneumeth.2018.05.022
Figure Lengend Snippet: A) FunRich analysis of cellular compartment enrichment in EV proteins identified using floatation- versus sedimentation-based isolation approaches. B) Relative spectral count abundance of common EV proteins and non-EV proteins in floatation- and sedimentation-isolated brain EV samples. C) Immunoblot analysis demonstrating enrichment of EV protein CD81 and depletion of Calnexin and HSC70 in floatation-isolated EVs. BH, brain homogenate. Float, floatation. Sed, sedimentation.
Article Snippet: Blots were probed with the following antibodies: Alix (Q-19; Santa Cruz Biotechnology),
Techniques: Sedimentation, Isolation, Western Blot